List of matches in this round
- TimeMatch
- August 19, 2022
- --:--West Leeds RUFC22:27Harrogate Pythons RUFC 1st XV
- August 25, 2022
- --:--West Park Leeds RUFC0:32Harrogate Pythons RUFC 1st XV
- September 3, 2022
- 3:00 pmWensleydale RUFC18:15Harrogate Pythons RUFC 1st XV
- September 10, 2022
- 3:00 pmHarrogate Pythons RUFC 1st XV27:22Wheatley Hills RUFC
- September 17, 2022
- 3:00 pmBaildon RUFC7:7 AbandonedHarrogate Pythons RUFC 1st XV
- September 24, 2022
- 3:00 pmHarrogate Pythons RUFC 1st XV25:0 WalkoverBarnsley RUFC
- October 1, 2022
- 3:00 pmYarnbury RFC15:34Harrogate Pythons RUFC 1st XV
- October 8, 2022
- 3:00 pmBaildon RUFC19:39Harrogate Pythons RUFC 1st XV
- October 15, 2022
- 3:00 pmLeeds Corinthians RUFC18:31Harrogate Pythons RUFC 1st XV
- October 22, 2022
- 3:00 pmHarrogate Pythons RUFC 1st XV32:18North Ribblesdale RUFC
- October 29, 2022
- 3:00 pmNorthallerton RUFC19:24Harrogate Pythons RUFC 1st XV
- November 5, 2022
- 2:15 pmHarrogate Pythons RUFC 1st XV22:6Bramley Phoenix RFC
- November 12, 2022
- 2:15 pmRipon RUFC3:15Harrogate Pythons RUFC 1st XV
- November 26, 2022
- 2:15 pmHarrogate Pythons RUFC 1st XV25:18Wath Upon Dearne RUFC
- December 3, 2022
- 2:15 pmWheatley Hills RUFC17:30Harrogate Pythons RUFC 1st XV
- December 10, 2022
- 2:15 pmHarrogate Pythons RUFC 1st XVPostponedBaildon RUFC
- December 17, 2022
- 2:15 pmHarrogate Pythons RUFC 1st XVHWOBarnsley RUFC
- January 7, 2023
- 2:15 pmHarrogate Pythons RUFC 1st XV29:19Yarnbury RFC
- January 14, 2023
- 2:15 pmHarrogate Pythons RUFC 1st XV31:7Leeds Corinthians RUFC
- January 21, 2023
- 2:15 pmNorth Ribblesdale RUFCPostponedHarrogate Pythons RUFC 1st XV
- January 28, 2023
- 2:15 pmHarrogate Pythons RUFC 1st XV50:7Northallerton RUFC
- February 4, 2023
- 2:15 pmHarrogate Pythons RUFC 1st XV15:30Baildon RUFC
- February 11, 2023
- 2:15 pmBramley Phoenix RFC28:27Harrogate Pythons RUFC 1st XV
- February 18, 2023
- 2:15 pmHarrogate Pythons RUFC 1st XV19:19Ripon RUFC
- March 4, 2023
- 3:00 pmWath Upon Dearne RUFC40:36Harrogate Pythons RUFC 1st XV
- March 18, 2023
- 3:00 pmNorth Ribblesdale RUFC20:26Harrogate Pythons RUFC 1st XV
- April 1, 2023
- 3:00 pmHarrogate Pythons RUFC 1st XV--:--Wensleydale RUFC
- April 8, 2023
- 3:00 pmHarrogate Pythons RUFC 1st XV30:29Wensleydale RUFC