List of matches in this round
- TimeMatch
- September 3, 2022
- 3:00 pmWensleydale RUFC 2nd XVMatch Abandoned (Injury)Harrogate Pythons RUFC 2nd XV
- September 10, 2022
- 3:00 pmWetherby RUFC 2nd XV63:12Harrogate Pythons RUFC 2nd XV
- September 24, 2022
- 3:00 pmBramley Phoenix RUFC 2nd XV7:36Harrogate Pythons RUFC 2nd XV
- October 1, 2022
- 3:00 pmHarrogate Pythons RUFC 2nd XV39:6Yarnbury RFC 3rd XV
- October 8, 2022
- 3:00 pmCastleford RUFC 2nd XV7:31Harrogate Pythons RUFC 2nd XV
- October 15, 2022
- 3:00 pmHarrogate Pythons RUFC 2nd XV33:17Leeds Corinthians RUFC 2nd XV
- October 22, 2022
- 3:00 pmNorth Ribblesdale RUFC 2nd XV41:3Harrogate Pythons RUFC 2nd XV
- November 12, 2022
- 2:15 pmHarrogate Pythons RUFC 2nd XV10:13Ripon RUFC 2nd XV
- November 19, 2022
- 2:15 pmHarrogate Pythons RUFC 2nd XVHWOBradford & Bingley RFC 2nd XV
- December 3, 2022
- 2:15 pmHarrogate Pythons RUFC 2nd XVHWOCastleford RUFC 2nd XV
- December 10, 2022
- 2:15 pmWest Park Leeds RUFC 2nd XVAWOHarrogate Pythons RUFC 2nd XV
- December 17, 2022
- 2:15 pmHarrogate Pythons RUFC 2nd XVPostponedYork RI RUFC 3rd XV
- January 7, 2023
- 2:15 pmYarnbury RFC 3rd XVAWOHarrogate Pythons RUFC 2nd XV
- January 14, 2023
- 2:15 pmLeeds Corinthians RUFC 2nd XV5:32Harrogate Pythons RUFC 2nd XV
- January 21, 2023
- 2:15 pmHarrogate Pythons RUFC 2nd XVPostponedNorth Ribblesdale RUFC 2nd XV
- February 4, 2023
- 2:15 pmRoundhegians RUFC 3rd XVAWOHarrogate Pythons RUFC 2nd XV
- February 11, 2023
- 2:15 pmHarrogate Pythons RUFC 2nd XV38:24Bramley Phoenix RUFC 2nd XV
- February 18, 2023
- 2:15 pmRipon RUFC 2nd XV13:12Harrogate Pythons RUFC 2nd XV
- February 25, 2023
- 2:15 pmYork RI RUFC 3rd XVAWOHarrogate Pythons RUFC 2nd XV
- March 4, 2023
- 3:00 pmHarrogate Pythons RUFC 2nd XVHWOIlkley RFC 3rd XV
- March 11, 2023
- 3:00 pmWensleydale RUFC 2nd XVPostponedHarrogate Pythons RUFC 2nd XV
- March 25, 2023
- 3:00 pmHarrogate Pythons RUFC 2nd XV--:--West Park Leeds RUFC 2nd XV
- April 1, 2023
- 3:00 pmHarrogate Pythons RUFC 2nd XV--:--Roundhegians RUFC 3rd XV
- 3:00 pmRoundhegians RUFC 3rd XV21:43Harrogate Pythons RUFC 2nd XV
- April 15, 2023
- 3:00 pmBradford & Bingley RFC 2nd XV--:--Harrogate Pythons RUFC 2nd XV
- April 22, 2023
- 3:00 pmHarrogate Pythons RUFC 2nd XV--:--Wetherby RUFC 2nd XV